![]() This paper also reports the N-terminus of the 15 most abundant venom proteins and the sequences matching their corresponding transcripts. A significant number of sequences were devoid of database matches, suggesting that their biologic function remains to be identified. gabonica venom proteins are also presented. The CLUSTAL alignment and the unrooted cladograms for selected families of B. In addition, we have identified for the first time a cytokine-like molecule and a multi-Kunitz protease inhibitor in snake venoms. ![]() Two new members of the recently described short coding region family of disintegrin, displaying RGD and MLD motifs are reported. ![]() We found mostly novel full-length cDNA coding for metalloproteases (P-II and P-III classes), Lys49-phospholipase A2, serine proteases with essential mutations in the active site, Kunitz protease inhibitors, several C-type lectins, bradykinin-potentiating peptide, vascular endothelial growth factor, nucleotidases and nucleases, nerve growth factor, and L-amino acid oxidases. Hundreds of cDNAs were obtained and clustered into contigs. The venom gland of the snake Bitis gabonica ( Gaboon viper) was used for the first time to construct a unidirectional cDNA phage library followed by high-throughput sequencing and bioinformatic analysis. My-Pham, Van Harrison, Jim Garfield, Mark K. Bitis gabonica ( Gaboon viper) snake venom gland: toward a catalog for the full- length transcripts (cDNA) and proteinsįrancischetti, Ivo M.
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